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Univariate Analysis of Demographic and Admission Characteristics of Patients Who Acquired Methicillin-Resistant Staphylococcus aureus during Hospitalization and Matched Control Patients

VariableCase patients (n = 451)Control patients (n = 866)OR (95% CI)P
Age, years, mean ± SD60.2 ± 17.559.2 ± 16.41.00 (1.00–1.01).35
Male sex250 (55.4)484 (55.9)0.95 (0.75–1.20).67
Race.98
 White330 (73.2)639 (73.8)1.00
 Black42 (9.3)79 (9.1)1.02 (0.69–1.52)
 Other or unknown79 (17.5)148 (17.1)1.02 (0.75–1.41)
Emergent or urgent admission401 (88.9)767 (88.6)1.06 (0.73–1.55).75
Admission from long-term care facility41 (9.1)51 (5.9)1.52 (0.99–2.35).06
Admitting service.52
 Medical260 (57.6)520 (60.0)1.00
 Surgical183 (40.6)329 (38.0)1.18 (0.88–1.58)
 Other8 (1.8)17 (2.0)0.92 (0.38–2.24)
LOS, days, median (IQR)30 (17–50)32 (20–54)1.00 (1.00–1.00).51
 Prior to index culture12 (6–24)13 (8–24)1.00 (1.00–1.00).98
 In target unit21 (12–35)21 (12–34)1.00 (1.00–1.00).29
Target unit stay prior to index culture447 (99.1)821 (94.8)6.27 (2.23–17.61)<.001
LOS in target unit prior to index culture, days, median (IQR)9 (5–18)10 (5–19)1.00 (1.00–1.00).65
Other UPMC hospitalization during past 6 months100 (22.2)241 (27.8)0.73 (0.56–0.95).02
Substance abuse or dependence
 Alcohol42 (9.3)95 (11.0)0.84 (0.57–1.23).37
 Drug23 (5.1)40 (4.6)1.16 (0.68–1.99).58
 Tobacco35 (7.8)72 (8.3)0.89 (0.58–1.38).61
Primary diagnosisa.08
 Cardiocirculatory disease51 (11.3)135 (15.6)1.00
 Respiratory disease100 (22.2)146 (16.9)2.00 (1.26–3.17)
 Digestive tract disease48 (10.7)86 (9.9)1.59 (0.94–2.68)
 Cerebrovascular disease38 (8.4)71 (8.2)1.64 (0.87–3.06)
 Injury or trauma98 (21.8)186 (21.5)1.54 (0.97–2.45)
 Other diagnosisb115 (25.6)242 (27.9)1.38 (0.89–2.15)
Age-adjusted Charlson comorbidity index, mean ± SD3.8 ± 2.94.0 ± 3.00.97 (0.93–1.01).13
Total point value assigned for abnormal laboratory values,c median (IQR)5 (4–6)5 (4–6)0.95 (0.87–1.03).18
Contact isolation for other target organism161 (35.7)339 (39.1)0.83 (0.64–1.07).14
Discharge disposition.15
 Alive286 (63.4)539 (62.2)1.00
 Deceased112 (24.8)193 (22.3)1.10 (0.83–1.46)
 Unknown53 (11.8)134 (15.5)0.74 (0.52–1.06)