Bp is high and k is low on the patient. this is an example of what type of specialized language?

1. Bakris GL, Williams M, Dworkin L, et al. Preserving renal function in adults with hypertension and diabetes: a consensus approach. National Kidney Foundation Hypertension and Diabetes Executive Committees Working Group. Am J Kidney Dis. 2000;36(3):646–661. [PubMed] [Google Scholar]

2. Lash JP, Go AS, Appel LJ, et al. Chronic Renal Insufficiency Cohort (CRIC) Study: baseline characteristics and associations with kidney function. Clin J Am Soc Nephrol. 2009;4(8):1302–1311. [PMC free article] [PubMed] [Google Scholar]

3. Egan BM, Zhao Y, Axon RN. US trends in prevalence, awareness, treatment, and control of hypertension, 1988–2008. JAMA. 2010;303(20):2043–2050. [PubMed] [Google Scholar]

4. Cai G, Zheng Y, Sun X, Chen X. Prevalence, awareness, treatment, and control of hypertension in elderly adults with chronic kidney disease: results from the survey of Prevalence, Awareness, and Treatment Rates in Chronic Kidney Disease Patients With Hypertension in China. J Am Geriatr Soc. 2013;61(12):2160–2167. [PubMed] [Google Scholar]

5. Tozawa M, Iseki K, Iseki C, Kinjo K, Ikemiya Y, Takishita S. Blood pressure predicts risk of developing end-stage renal disease in men and women. Hypertension. 2003;41(6):1341–1345. [PubMed] [Google Scholar]

6. Klag MJ, Whelton PK, Randall BL, et al. Blood pressure and end-stage renal disease in men. N Engl J Med. 1996;334(1):13–18. [PubMed] [Google Scholar]

7. Parati G, Stergiou G, O’Brien E, et al. European Society of Hypertension practice guidelines for ambulatory blood pressure monitoring. J Hypertens. 2014;32(7):1359–1366. [PubMed] [Google Scholar]

8. Mancia G, Fagard R, Narkiewicz K, et al. 2013 ESH/ESC guidelines for the management of arterial hypertension: the Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC) Eur Heart J. 2013;34(28):2159–2219. [PubMed] [Google Scholar]

9. Pogue V, Rahman M, Lipkowitz M, et al. Disparate estimates of hypertension control from ambulatory and clinic blood pressure measurements in hypertensive kidney disease. Hypertension. 2009;53(1):20–27. [PubMed] [Google Scholar]

10. Bangash F, Agarwal R. Masked hypertension and white-coat hypertension in chronic kidney disease: a meta-analysis. Clin J Am Soc Nephrol. 2009;4(3):656–664. [PMC free article] [PubMed] [Google Scholar]

11. Cha RH, Kim S, Ae Yoon S, et al. Association between blood pressure and target organ damage in patients with chronic kidney disease and hypertension: results of the APrODiTe study. Hypertens Res. 2014;37(2):172–178. [PubMed] [Google Scholar]

12. Minutolo R, Gabbai FB, Agarwal R, et al. Assessment of achieved clinic and ambulatory blood pressure recordings and outcomes during treatment in hypertensive patients with CKD: a multicenter prospective cohort study. Am J Kidney Dis. 2014;64(5):744–752. [PubMed] [Google Scholar]

13. Boggia J, Li Y, Thijs L, et al. Prognostic accuracy of day versus night ambulatory blood pressure: a cohort study. Lancet. 2007;370(9594):1219–1229. [PubMed] [Google Scholar]

14. Liu M, Takahashi H, Morita Y, et al. Non-dipping is a potent predictor of cardiovascular mortality and is associated with autonomic dysfunction in haemodialysis patients. Nephrol Dial Transplant. 2003;18(3):563–569. [PubMed] [Google Scholar]

15. Minutolo R, Agarwal R, Borrelli S, et al. Prognostic role of ambulatory blood pressure measurement in patients with nondialysis chronic kidney disease. Arch Intern Med. 2011;171(12):1090–1098. [PubMed] [Google Scholar]

16. Haruhara K, Tsuboi N, Koike K, et al. Renal histopathological findings in relation to ambulatory blood pressure in chronic kidney disease patients. Hypertens Res. 2014 [e-pub ahead of print, 2014 Sep 18.]. http://dx.doi.org/10.1038/hr.2014.140. [PubMed] [Google Scholar]

17. Mojon A, Ayala DE, Pineiro L, et al. Comparison of ambulatory blood pressure parameters of hypertensive patients with and without chronic kidney disease. Chronobiol Int. 2013;30(1–2):145–158. [PubMed] [Google Scholar]

18. Hermida RC, Smolensky MH, Ayala DE, et al. Abnormalities in chronic kidney disease of ambulatory blood pressure 24 h patterning and normalization by bedtime hypertension chronotherapy. Nephrol Dial Transplant. 2014;29(6):1160–1167. [PubMed] [Google Scholar]

19. Agarwal R, Andersen MJ. Correlates of systolic hypertension in patients with chronic kidney disease. Hypertension. 2005;46(3):514–520. [PubMed] [Google Scholar]

20. Higashi Y, Oshima T, Ozono R, et al. Nocturnal decline in blood pressure is attenuated by NaCl loading in salt-sensitive patients with essential hypertension: noninvasive 24-hour ambulatory blood pressure monitoring. Hypertension. 1997;30(2 Pt 1):163–167. [PubMed] [Google Scholar]

21. Uzu T, Sakaguchi M, Yokomaku Y, et al. Effects of high sodium intake and diuretics on the circadian rhythm of blood pressure in type 2 diabetic patients treated with an angiotensin II receptor blocker. Clin Exp Nephrol. 2009;13(4):300–306. [PubMed] [Google Scholar]

22. Townsend RR, Wimmer NJ, Chirinos JA, et al. Aortic PWV in chronic kidney disease: a CRIC ancillary study. Am J Hypertens. 2010;23(3):282–289. [PMC free article] [PubMed] [Google Scholar]

23. Gates PE, Tanaka H, Hiatt WR, Seals DR. Dietary sodium restriction rapidly improves large elastic artery compliance in older adults with systolic hypertension. Hypertension. 2004;44(1):35–41. [PubMed] [Google Scholar]

24. Logan AG, Perlikowski SM, Mente A, et al. High prevalence of unrecognized sleep apnoea in drug-resistant hypertension. J Hypertens. 2001;19(12):2271–2277. [PubMed] [Google Scholar]

25. Sakaguchi Y, Shoji T, Kawabata H, et al. High prevalence of obstructive sleep apnea and its association with renal function among non-dialysis chronic kidney disease patients in Japan: a cross-sectional study. Clin J Am Soc Nephrol. 2011;6(5):995–1000. [PMC free article] [PubMed] [Google Scholar]

26. Langstan JB, Guyton AC, Douglas BH, Dorsett PE, Russel A, McCaa RE. Effect of changes in salt intake on arterial pressure and renal function in partially nephrectomized dogs. Circ Res. 1963;12:508–513. [Google Scholar]

27. Guyton AC. Blood pressure control—special role of the kidneys and body fluids. Science. 1991;252(5014):1813–1816. [PubMed] [Google Scholar]

28. Ying WZ, Sanders PW. Dietary salt modulates renal production of transforming growth factor-beta in rats. Am J Physiol. 1998;274(4 Pt 2):F635–F641. [PubMed] [Google Scholar]

29. Fellner RC, Cook AK, O’Connor PM, Zhang S, Pollock DM, Inscho EW. High-salt diet blunts renal autoregulation by a reactive oxygen species-dependent mechanism. Am J Physiol Renal Physiol. 2014;307(1):F33–F40. [PMC free article] [PubMed] [Google Scholar]

30. Smyth A, O’Donnell MJ, Yusuf S, et al. Sodium intake and renal outcomes: a systematic review. Am J Hypertens. 2014;27(10):1277–1284. [PubMed] [Google Scholar]

31. American Diabetes Associations. Standards of medical care in diabetes— 2013. Diabetes Care. 2013;36(suppl 1):S11–S66. [PMC free article] [PubMed] [Google Scholar]

32. 2013 Practice guidelines for the management of arterial hypertension of the European Society of Hypertension (ESH) and the European Society of Cardiology (ESC): ESH/ESC Task Force for the Management of Arterial Hypertension. J Hypertens. 2013;31(10):1925–1938. [PubMed] [Google Scholar]

33. Go AS, Bauman MA, Coleman King SM, et al. An effective approach to high blood pressure control: a science advisory from the American Heart Association, the American College of Cardiology, and the Centers for Disease Control and Prevention. Hypertension. 2014;63(4):878–885. [PubMed] [Google Scholar]

34. Group KDIGOKBPW. Clinical practice guideline for the evaluation and management of blood pressure in chronic kidney disease. Kidney Int Suppl. 2012;2(5):337–414. [Google Scholar]

35. James PA, Oparil S, Carter BL, et al. 2014 evidence-based guideline for the management of high blood pressure in adults report from the panel members appointed to the Eighth Joint National Committee (JNC 8) JAMA. 2014;311(5):507–520. [PubMed] [Google Scholar]

36. Krause T, Lovibond K, Caulfield M, McCormack T, Williams B. Management of hypertension: summary of NICE guidance. BMJ. 2011;343:d4891. [PubMed] [Google Scholar]

37. Weber MA, Schiffrin EL, White WB, et al. Clinical practice guidelines for the management of hypertension in the community: a statement by the American Society of Hypertension and the International Society of Hypertension. J Clin Hypertens (Greenwich) 2014;16(1):14–26. [PMC free article] [PubMed] [Google Scholar]

38. Taler SJ, Agarwal R, Bakris GL, et al. KDOQI US commentary on the 2012 KDIGO clinical practice guideline for management of blood pressure in CKD. Am J Kidney Dis. 2013;62(2):201–213. [PMC free article] [PubMed] [Google Scholar]

39. Upadhyay A, Earley A, Haynes SM, Uhlig K. Systematic review: blood pressure target in chronic kidney disease and proteinuria as an effect modifier. Ann Intern Med. 2011;154(8):541–548. [PubMed] [Google Scholar]

40. Kovesdy CP, Bleyer AJ, Molnar MZ, et al. Blood pressure and mortality in U.S. veterans with chronic kidney disease: a cohort study. Ann Intern Med. 2013;159(4):233–242. [PMC free article] [PubMed] [Google Scholar]

41. Calhoun DA, Jones D, Textor S, et al. Resistant hypertension: diagnosis, evaluation, and treatment. A scientific statement from the American Heart Association Professional Education Committee of the Council for High Blood Pressure Research. Hypertension. 2008;51(6):1403–1419. [PubMed] [Google Scholar]

42. Bax L, Woittiez AJ, Kouwenberg HJ, et al. Stent placement in patients with atherosclerotic renal artery stenosis and impaired renal function: a randomized trial. Ann Intern Med. 2009;150(12):840–848. w150–w841. [PubMed] [Google Scholar]

43. Wheatley K, Ives N, Gray R, et al. Revascularization versus medical therapy for renal-artery stenosis. N Engl J Med. 2009;361(20):1953–1962. [PubMed] [Google Scholar]

44. Cooper CJ, Murphy TP, Cutlip DE, et al. Stenting and medical therapy for atherosclerotic renal-artery stenosis. N Engl J Med. 2014;370(1):13–22. [PMC free article] [PubMed] [Google Scholar]

45. McMahon EJ, Bauer JD, Hawley CM, et al. A randomized trial of dietary sodium restriction in CKD. J Am Soc Nephrol. 2013;24(12):2096–2103. [PMC free article] [PubMed] [Google Scholar]

46. Slagman MC, Waanders F, Hemmelder MH, et al. Moderate dietary sodium restriction added to angiotensin converting enzyme inhibition compared with dual blockade in lowering proteinuria and blood pressure: randomised controlled trial. BMJ. 2011;343:d4366. [PMC free article] [PubMed] [Google Scholar]

47. Vogt L, Waanders F, Boomsma F, de Zeeuw D, Navis G. Effects of dietary sodium and hydrochlorothiazide on the anti-proteinuric efficacy of losartan. J Am Soc Nephrol. 2008;19(5):999–1007. [PMC free article] [PubMed] [Google Scholar]

48. Institute of Medicine. Sodium Intake in Populations: Assessment of Evidence. Washington, DC: The National Academies Press; 2013. [Google Scholar]

49. Anderson CA, Ix JH. Sodium reduction in CKD: suggestively hazardous or intuitively advantageous? J Am Soc Nephrol. 2013;24(12):1931–1933. [PMC free article] [PubMed] [Google Scholar]

50. Agarwal R, Sinha AD. Thiazide diuretics in advanced chronic kidney disease. J Am Soc Hypertens. 2012;6(5):299–308. [PubMed] [Google Scholar]

51. Dussol B, Moussi-Frances J, Morange S, Somma-Delpero C, Mundler O, Berland Y. A pilot study comparing furosemide and hydrochlorothiazide in patients with hypertension and stage 4 or 5 chronic kidney disease. J Clin Hypertens (Greenwich) 2012;14(1):32–37. [PMC free article] [PubMed] [Google Scholar]

52. Carter BL, Ernst ME, Cohen JD. Hydrochlorothiazide versus chlorthalidone: evidence supporting their interchangeability. Hypertension. 2004;43(1):4–9. [PubMed] [Google Scholar]

53. Crespo JJ, Pineiro L, Otero A, et al. Administration-time-dependent effects of hypertension treatment on ambulatory blood pressure in patients with chronic kidney disease. Chronobiol Int. 2013;30(1–2):159–175. [PubMed] [Google Scholar]

54. Hermida RC, Ayala DE. Chronotherapy with the angiotensin-converting enzyme inhibitor ramipril in essential hypertension: improved blood pressure control with bedtime dosing. Hypertension. 2009;54(1):40–46. [PubMed] [Google Scholar]

55. Hermida RC, Ayala DE, Mojon A, Fernandez JR. Influence of circadian time of hypertension treatment on cardiovascular risk: results of the MAPEC study. Chronobiol Int. 2010;27(8):1629–1651. [PubMed] [Google Scholar]

56. Hermida RC, Ayala DE, Mojon A, Fernandez JR. Bedtime dosing of antihypertensive medications reduces cardiovascular risk in CKD. J Am Soc Nephrol. 2011;22(12):2313–2321. [PMC free article] [PubMed] [Google Scholar]

57. Hermida RC, Ayala DE, Mojon A, Fernandez JR. Influence of time of day of blood pressure-lowering treatment on cardiovascular risk in hypertensive patients with type 2 diabetes. Diabetes Care. 2011;34(6):1270–1276. [PMC free article] [PubMed] [Google Scholar]

58. Chapman N, Dobson J, Wilson S, et al. Effect of spironolactone on blood pressure in subjects with resistant hypertension. Hypertension. 2007;49(4):839–845. [PubMed] [Google Scholar]

59. Vaclavik J, Sedlak R, Plachy M, et al. Addition of spironolactone in patients with resistant arterial hypertension (ASPIRANT): a randomized, double-blind, placebo-controlled trial. Hypertension. 2011;57(6):1069–1075. [PubMed] [Google Scholar]

60. Pisoni R, Acelajado MC, Cartmill FR, et al. Long-term effects of aldosterone blockade in resistant hypertension associated with chronic kidney disease. J Hum Hypertens. 2012;26(8):502–506. [PMC free article] [PubMed] [Google Scholar]

61. Shavit L, Lifschitz MD, Epstein M. Aldosterone blockade and the mineralocorticoid receptor in the management of chronic kidney disease: current concepts and emerging treatment paradigms. Kidney Int. 2012;81(10):955–968. [PubMed] [Google Scholar]

62. Judd E, Calhoun DA. Apparent and true resistant hypertension: definition, prevalence and outcomes. J Hum Hypertens. 2014;28(8):463–468. [PMC free article] [PubMed] [Google Scholar]


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Definition of Terms Associated With Hypertension

Hypertensive TermDefinitionComments
Resistant hypertensionUncontrolled BP despite maximal effective dosing of ≥3 medications of different classes, one ideally being a diuretic41Includes patients controlled on ≥4 medications
Apparent resistant hypertensionMeeting criteria for resistant HTN, yet unable to exclude pseudoresistance62Reported in observational studies
PseudoresistanceUncontrolled office BP while receiving ≥3 medications in the setting of medication nonadherence, improper BP measurement technique, and/or white coat HTNPresumed to contribute to as much as 50% of resistant hypertension62
White coat hypertensionUncontrolled office BP with a controlled overall average BP by 24-hr ABPM (<130/80 mm Hg) or home BP < 135/85 mm Hg7
Masked uncontrolled hypertensionControlled office BP (<140/90 mm Hg) with an elevated overall average BP by 24-hr ABPM (>130/80 mm Hg) or home BP > 135/85 mm Hg7Present in as many as 40%–70% of patients with CKD and HTN9,10
DippingFall in nocturnal systolic and diastolic BP of >10% of daytime values7
Nondipping and risingNo reduction or an increase in nocturnal systolic and/or diastolic BP7
Refractory hypertensionUncontrolled BP despite maximal medical therapy (ie, ≥5 antihypertensive medications at maximal effective dosing and of different class)