When two chemicals together have an effect that is greater than the sum of their individual effects then they are said to work in an mode?

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Page 2

1. Predictions with different approaches for combining stressors: Stress-Addition according to the Multi-TOX approach (SA), effect-addition (EA) and concentration-addition (CA). Whole curve estimates of combined toxicant effect: root mean square error (RMSE). Point estimate (LC50) of combined toxicant effect: model deviation ratio (MDR)
2. aSA (stress addition) calculated according to the Multi-TOX approach. For low food 81% SA, for high food 38% SA
3. bObserved LC50 calculated with the mean survival of all experimental repetitions, fitted with ECx-SyS
4. cPredicted LC50 based on the concentration–response relationships of single toxicants modeled with stress addition according to the Multi-TOX approach
5. dMDR values are calculated by dividing the predicted LC50 of SA, CA, EA by the observed LC50. For values of CA > 2, interactions between stressors are interpreted as synergistic related to CA